The Optimizing Pediatric HIV-1 Therapy (OPH) Project
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The Optimizing Pediatric HIV-1 Therapy (OPH) Project is a collaborative study conducted by the University of Nairobi Department of Paediatrics and Child Health and the University of Washington department of Global Health. The objectives of the OPH study are:

Primary Objective

To compare growth and morbidity in infants (who initiated HAART at <12 months of age with subsequently normalized CD4% and growth following 24 months of HAART) randomized to deferred versus continuous therapy and followed for an additional 18 months.

Secondary Objective

To determine predictors of non-progression of HIV among the infants, including: age, adherence, HIV-1 specific immune responses, baseline HIV-1 RNA, CD4 percent and immune activation.







500,000 USD
Start Year: 
End Year: